Endocrine Abstracts

Purpose: To investigate the carbohydrate metabolism in depend on acromegaly treatment.Material and methods: 23 patients with newly diagnosed acromegaly (NA) were observed. Carbohydrate metabolism were investigated after somatostatine analogues treatment (SSA) (14 patients) or after surgery (TSA) (9 patients). Groups were comparable on age, BMI, acromegaly duration. Were researched HbA1c, fasting plasma glucose level (FPG), indexes of insulin resistance (...

Aim: To evaluate the frequency and morpho-histological characteristics of the colonic polyps (CP) in acromegaly patients (pts).Materials and methods: We studied 53 pts (50 female, 3 men) aged 23–76 (median – 47) with active acromegaly. The mean disease duration was 10.7±4.3 years. Somatotropinoma was diagnosed in 51 pts and somatoprolactinoma in two. The activity of acromegal? was confirmed on the base of the clinical and hormonal data. Ba...

Aim: To estimate efficiency of long acting somatostatin analog (Oktreotid-Depot, Ltd ‘FarmSyntez’, Russia) in acromegaly treatment.Material and methods: Twenty-five patients with the confirmed acromegaly diagnosis, active phase, receiving Oktreotid-Depot therapy within 6–12 months in a single dose of 20–40 mg/month. Every three months dynamics of clinical signs, basal IGF-1 and GH levels and pituitary adenoma size were analyzed.<p...